Drug interactions may perhaps modify how your drugs operate or enhance your risk for severe Unintended effects. This document won't include all doable drug interactions.
Postmarketing instances of respiratory melancholy, which include fatalities have already been documented with utilization of promethazine in pediatric people.
Do not give this medication to everyone younger than eighteen a long time previous who recently experienced operation to get rid of the tonsils or adenoids.
To lessen the potential risk of dizziness and lightheadedness, stand up slowly but surely when climbing from a sitting or lying placement.
Clinical Factors Fetal/Neonatal Adverse Reactions Extended usage of opioid analgesics all through pregnancy for clinical or nonmedical needs may end up in Actual physical dependence from the neonate and neonatal opioid withdrawal syndrome Soon after birth.
Tend not to raise your dose or use this products extra generally or for for a longer period than prescribed. Your affliction will likely not boost any speedier, plus your hazard of Uncomfortable side effects will raise.
If a person has overdosed and has really serious indications including passing out or hassle breathing, phone 911. If not, get in touch with a poison Regulate Centre straight away.
Promethazine with Codeine Oral Solution has promethazine, a phenothiazine. Phenothiazines are linked with dystonic reactions, especially in pediatric people who may have an read more acute disease affiliated with dehydration.
This isn't a whole list of achievable Unintended effects. For those who observe other Uncomfortable side effects not stated earlier mentioned, Get hold of your doctor or pharmacist.
Use with caution in people with fundamental intestinal motility Diseases. The codeine in Promethazine with Codeine Oral Alternative may well trigger spasm of your sphincter of Oddi, causing an increase in biliary tract tension. Opioids may well lead to raises in serum amylase [seeWARNINGS AND Safety measures (5.21)]. Monitor clients with biliary tract condition, which includes acute pancreatitis for worsening signs. Administration of promethazine has been affiliated with noted cholestatic jaundice.
Employ other supportive measures (which include oxygen and vasopressors) within the management of circulatory shock and pulmonary edema as indicated. Cardiac arrest or arrhythmias would require advanced existence-guidance techniques. Gastric emptying could possibly be practical in removing unabsorbed drug.
Promethazine is extensively dispersed in overall body tissues. Promethazine has higher protein binding with about 80 to 93% of promethazine certain to plasma proteins. Promethazine passes the blood brain barrier as well as placental barrier.
Get this medication by mouth with or without meals as directed by your medical doctor, generally each four to six hrs as necessary. This medication may be taken with food if tummy upset happens. Drink loads of fluids any time you use this medication Except if in any other case directed by your medical doctor.
In advance of using this medication, notify your physician or pharmacist For anyone who is allergic to any of its elements; or to opioid pain relievers (which include morphine); or if you have any other allergies.